What is your full name, job title and where do you work?
I'm Luigi Mari, a Postdoctoral Research Associate in Dept. of Immunology at St. Jude Children's Research Hospital in Memphis.
What are your main research interests?
Understanding basic mechanisms of tumor immunology to improve cancer immunotherapy.
Describe your work in a tweet
Exploring innate and adaptive immunity to boost anti-tumor immune response
What big projects are you working on right now?
I am currently focusing on basic mechanisms of antigen presentation in the context of anti-tumor immunity.
Who do you collaborate with?
Any scientist that is willing to share on behalf of scientific progress
Tell us a bit about your career so far
Graduated in Medical Biotechnology at the University of Perugia (Italy). Then obtained a PhD in tumor biology at the Academic Medical Center in Amsterdam (The Netherlands). Currently post-doc at St. Jude Children’s Research Hospital.
What are you most proud of?
I am proud of my achievements during the PhD that led to the discovering of novel mechanisms of tumor immune-evasion.
What’s your interest in the Cancer Immune Setpoint?
There is a urgent need of a platform where scientists can have an immediate overview of the different aspects that influences a response to immunotherapy
What do you hope it will achieve?
I hope it will be a reference for both scientists and clinicians in order to improve personalized therapies
What are your hopes for the future of cancer immunotherapy?
I hope that the recent progress in the sequencing field will combine to the novel immunotherapeutic drugs to provide soon a platform for decision making by clinicians.
What advice do you have for others working in the field?
I would advise to think wider instead of focusing on single molecules. Both for therapy and biomarkers. In fact, it is now clear that a good response to immunotherapy depends on several factors of the tumor microenvironment.
What do you do to wind down?
I do photography, play soccer and travel with my family.
Tell us something unusual about yourself
I would love to work in a lab in front of the sea
Are you interested in having your profile featured?
Evolving the cancer-immune setpoint can only happen with the help of our members. Keeping it up to date, improving on what’s included and adding new data that are being published all the time can only be achieved through a collective effort.
So we’re incredibly grateful to all of our members who are contributing. As a reward, you may be able to feature in a Q&A post. These profiles are highlighted to all members of our community (there’s over 1,000 of us now!), so it’s a really great way to raise your profile among your peers!
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